BDBM624501 US11780849, Compound 54b
SMILES COc1cc2ncnc(N3CCC4(CCN(C4)[S@](C)(=N)=O)CC3)c2cc1OC
InChI Key InChIKey=PVOHNWPHNCCMLU-NDEPHWFRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 624501
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics
US Patent
Volastra Therapeutics
US Patent
Affinity DataKi: <3nMAssay Description:Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics
US Patent
Volastra Therapeutics
US Patent
Affinity DataKi: 1.30E+3nMAssay Description:Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics
US Patent
Volastra Therapeutics
US Patent
Affinity DataIC50: 7.60E+3nMAssay Description:Assay 1: Test compounds were plated in a 3 dilution scheme in a 384 well plate. To 50 nL of test compound in DMSO was added 2.5 μL ENPP-1 ECD in...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics
US Patent
Volastra Therapeutics
US Patent
Affinity DataIC50: <10nMAssay Description:Assay 1: Test compounds were plated in a 3 dilution scheme in a 384 well plate. To 50 nL of test compound in DMSO was added 2.5 μL ENPP-1 ECD in...More data for this Ligand-Target Pair