BDBM624512 US11780849, Compound 74::imino(4-(((7-methoxyquinolin-4- yl)amino)methyl)phenyl)(methyl)-lambda6-sulfanone

SMILES COc1ccc2c(NCc3ccc(cc3)S(C)(=N)=O)ccnc2c1

InChI Key InChIKey=GRSMRBCHOJYRBR-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 624512   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics

US Patent
LigandPNGBDBM624512(US11780849, Compound 74 | imino(4-(((7-methoxyquin...)
Affinity DataKi: <3nMAssay Description:Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics

US Patent
LigandPNGBDBM624512(US11780849, Compound 74 | imino(4-(((7-methoxyquin...)
Affinity DataKi:  1.70E+3nMAssay Description:Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics

US Patent
LigandPNGBDBM624512(US11780849, Compound 74 | imino(4-(((7-methoxyquin...)
Affinity DataIC50:  1.10E+4nMAssay Description:Assay 1: Test compounds were plated in a 3 dilution scheme in a 384 well plate. To 50 nL of test compound in DMSO was added 2.5 μL ENPP-1 ECD in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics

US Patent
LigandPNGBDBM624512(US11780849, Compound 74 | imino(4-(((7-methoxyquin...)
Affinity DataIC50:  505nMAssay Description:Assay 1: Test compounds were plated in a 3 dilution scheme in a 384 well plate. To 50 nL of test compound in DMSO was added 2.5 μL ENPP-1 ECD in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent