BDBM624579 US11780849, Compound 150::{2-[1-(6-fluoro-7-methoxyquinolin-4- yl)piperidin-4-yl]ethyl}(imino)methyl-lambda6- sulfanone
SMILES COc1cc2nccc(N3CCC(CCS(C)(=N)=O)CC3)c2cc1F
InChI Key InChIKey=DBHJKSALYGRLCJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 624579
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics
US Patent
Volastra Therapeutics
US Patent
Affinity DataKi: <3nMAssay Description:Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics
US Patent
Volastra Therapeutics
US Patent
Affinity DataKi: 1.30E+3nMAssay Description:Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics
US Patent
Volastra Therapeutics
US Patent
Affinity DataIC50: 8.60E+3nMAssay Description:Assay 1: Test compounds were plated in a 3 dilution scheme in a 384 well plate. To 50 nL of test compound in DMSO was added 2.5 μL ENPP-1 ECD in...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics
US Patent
Volastra Therapeutics
US Patent
Affinity DataIC50: <10nMAssay Description:Assay 1: Test compounds were plated in a 3 dilution scheme in a 384 well plate. To 50 nL of test compound in DMSO was added 2.5 μL ENPP-1 ECD in...More data for this Ligand-Target Pair