BDBM624590 US11780849, Compound 159::[8-(6,7-dimethoxyquinazolin-4-yl)-2,8- diazaspiro[4.5]decan-2-yl](ethyl)imino-lambda6- sulfanone

SMILES CCS(=N)(=O)N1CCC2(C1)CCN(CC2)c1ncnc2cc(OC)c(OC)cc12

InChI Key InChIKey=COUOZQLEVHVWJG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624590   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics

US Patent
LigandPNGBDBM624590(US11780849, Compound 159 | [8-(6,7-dimethoxyquinaz...)
Affinity DataKi: <3nMAssay Description:Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics

US Patent
LigandPNGBDBM624590(US11780849, Compound 159 | [8-(6,7-dimethoxyquinaz...)
Affinity DataKi:  25nMAssay Description:Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent