BDBM624591 US11780849, Compound 160::{cyclopropyl[8-(6,7-dimethoxyquinazolin-4- yl)-2,8-diazaspiro[4.5]decan-2-yl]imino-lambda6- sulfanyl}one

SMILES COc1cc2ncnc(N3CCC4(CCN(C4)S(=N)(=O)C4CC4)CC3)c2cc1OC

InChI Key InChIKey=SZIKREBUJFSXLW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624591   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics

US Patent
LigandPNGBDBM624591(US11780849, Compound 160 | {cyclopropyl[8-(6,7-dim...)
Affinity DataKi: <3nMAssay Description:Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Volastra Therapeutics

US Patent
LigandPNGBDBM624591(US11780849, Compound 160 | {cyclopropyl[8-(6,7-dim...)
Affinity DataKi:  21nMAssay Description:Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent