BDBM624953 US20230322745, Compound 24

SMILES O[C@@H](CNCc1cc2nnn(CCCN3CCC4(C[C@H](CO4)OC(=O)C(O)(c4cccs4)c4cccs4)CC3)c2c2CCCc12)c1ccc(O)c2[nH]c(=O)ccc12

InChI Key

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 624953   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624953(US20230322745, Compound 24)
Affinity DataEC50:  158nMAssay Description:β1 cells (expressing human ADRB1 gene) from ICE Bioscience Inc. were grown under standard conditions. The cells were collected and diluted with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624953(US20230322745, Compound 24)
Affinity DataIC50:  0.0140nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624953(US20230322745, Compound 24)
Affinity DataIC50:  0.220nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent