BDBM625179 2-(4-fluorophenyl)-N-[4-(5-methyl-4-oxo-3-phenyl-4,5-dihydro-1H-pyrrolo[3,2-c]pyridin-2-yl)pyridin-2-yl]acetamide::US20230322767, Example 5

SMILES Cn1ccc2[nH]c(c(-c3ccccc3)c2c1=O)-c1ccnc(NC(=O)Cc2ccc(F)cc2)c1

InChI Key InChIKey=FHPAOPMOHMSKCE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 625179   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625179(2-(4-fluorophenyl)-N-[4-(5-methyl-4-oxo-3-phenyl-4...)
Affinity DataIC50: >2.00E+4nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetcsnk1d(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625179(2-(4-fluorophenyl)-N-[4-(5-methyl-4-oxo-3-phenyl-4...)
Affinity DataIC50:  2.5nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1D, expressed by baculovirus infected insect cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625179(2-(4-fluorophenyl)-N-[4-(5-methyl-4-oxo-3-phenyl-4...)
Affinity DataIC50:  0.860nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent