BDBM625216 N-[4-(7,7-dimethyl-4-oxo-3-phenyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl)pyridin-2-yl]-2-(4-fluorophenyl)acetamide::US20230322767, Example 42

SMILES CC1(C)CNC(=O)c2c1[nH]c(c2-c1ccccc1)-c1ccnc(NC(=O)Cc2ccc(F)cc2)c1

InChI Key InChIKey=DZHGIWMUVYYVFJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 625216   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625216(N-[4-(7,7-dimethyl-4-oxo-3-phenyl-4,5,6,7-tetrahyd...)
Affinity DataIC50:  5.60E+3nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetcsnk1d(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625216(N-[4-(7,7-dimethyl-4-oxo-3-phenyl-4,5,6,7-tetrahyd...)
Affinity DataIC50:  2.10nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1D, expressed by baculovirus infected insect cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625216(N-[4-(7,7-dimethyl-4-oxo-3-phenyl-4,5,6,7-tetrahyd...)
Affinity DataIC50:  1.20nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent