BDBM625599 US20230322822, Compound 24
SMILES CN1CCN(CC1)C1CCN(CC1)c1cc(OC(F)F)c(Nc2ncc(Br)c(Nc3ccc(C)cc3P(C)(C)=O)n2)cc1C
InChI Key InChIKey=DCIRFDAZRWVBTR-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 625599
TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Homo sapiens (Human))
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 41.6nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [L858R,T790M,C797S](Homo sapiens (Human))
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 54nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
Targetegfr-c797s/ t790m/del19(Homo sapiens (Human))
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 24.5nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 887nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Homo sapiens (Human))
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 41.6nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [L858R,T790M,C797S](Homo sapiens (Human))
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 54nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
Targetegfr-c797s/ t790m/del19(Homo sapiens (Human))
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 24.5nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,T790M](Homo sapiens (Human))
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 23.5nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair