BDBM626323 US11787775, Compound 8::methyl 2-[[[4-cyano-7-(4- isopropylphenyl)-2,3- dihydrobenzofuran-5- yl]amino]methyl]prop-2-enoate
SMILES COC(=O)C(=C)CNc1cc(c2OCCc2c1C#N)-c1ccc(cc1)C(C)C
InChI Key InChIKey=MAHDYSBIRDPXDH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 626323
Affinity DataIC50: 70nMAssay Description:Table 2-3: His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid p...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Table 2-3: His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid p...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Table 2-3: His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid p...More data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-3/Isoform 5 of Transcriptional coactivator [50-100](Human)
Genentech
US Patent
Genentech
US Patent
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-1/Isoform 5 of Transcriptional coactivator [50-100](Human)
Genentech
US Patent
Genentech
US Patent
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-4/Isoform 5 of Transcriptional coactivator [50-100](Human)
Genentech
US Patent
Genentech
US Patent
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-5/Isoform 5 of Transcriptional coactivator [50-100](Human)
Genentech
US Patent
Genentech
US Patent
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Table 2-3: His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid p...More data for this Ligand-Target Pair