BDBM627513 N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-morpholinocyclohexyl)-1H-pyrazolo[4,3-c]pyridin-3-yl)-2,5-difluorophenyl)-2-chloro-5-ethoxybenzenesulfonamide::US20230331719, Compound A17
SMILES CCOc1ccc(Cl)c(c1)S(=O)(=O)Nc1cc(F)c(cc1F)-c1nn(C(C)C)c2c(cnc(N)c12)[C@H]1CC[C@@H](CC1)N1CCOCC1
InChI Key InChIKey=SYELSIWJXRYYNQ-MEMLXQNLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 627513
Affinity DataIC50: 2.10nMAssay Description:The RNase reactions were performed in 384 well black ProxiPlate-384 Plus plates (PERKIN Elmer) using 50 mM Tris assay buffer with 0.5 mM MgCl2, 10 mM...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair