BDBM629251 (+)-2-(4-fluorophenyl)-N-[4-(3-phenyl-1H-pyrrolo[3,2-b]pyridin-2-yl)pyridin-2-yl]propanamide (Enantiomer 2)::US20230339939, Example 13

SMILES CC(C(=O)Nc1cc(ccn1)-c1[nH]c2cccnc2c1-c1ccccc1)c1ccc(F)cc1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 629251   

TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629251((+)-2-(4-fluorophenyl)-N-[4-(3-phenyl-1H-pyrrolo[3...)
Affinity DataIC50:  1.66nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629251((+)-2-(4-fluorophenyl)-N-[4-(3-phenyl-1H-pyrrolo[3...)
Affinity DataIC50: >2.00E+4nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM629251((+)-2-(4-fluorophenyl)-N-[4-(3-phenyl-1H-pyrrolo[3...)
Affinity DataIC50:  91.6nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent