BDBM629475 US20230339981, Example 163

SMILES Oc1cc(-c2nc3CC[C@@H]4[C@@H]5CC[C@H](CN4c4nc(OC[C@@]67CCCN6[C@H](COCC(F)(F)F)CC7)nc(c2F)c34)N5)c2c(C#C)c(F)ccc2c1

InChI Key InChIKey=MPXQXRLXVPDMSO-UDGXGKHASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 629475   

TargetGTPase KRas [G12D](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM629475(US20230339981, Example 163)
Affinity DataIC50:  0.100nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent