BDBM632545 (2R,3R,4S,5R,6R)-2-((3-chloro-5-cyanophenyl)((1S,2S)-2- hydroxycyclopentyl)carbamoyl)-4-(4-(3,5-difluoro-4-methylphenyl)-1H-1,2,3- triazol-1-yl)-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl acetate::US20230348442, Example 1A.4.4

SMILES CC(=O)O[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1cc(F)c(C)c(F)c1)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Cl)cc(c1)C#N

InChI Key InChIKey=JVOMJMWDCZZZJB-VHUHOHQYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 632545   

TargetGalectin-3(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM632545((2R,3R,4S,5R,6R)-2-((3-chloro-5-cyanophenyl)((1S,2...)
Affinity DataIC50:  26.8nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGalectin-1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM632545((2R,3R,4S,5R,6R)-2-((3-chloro-5-cyanophenyl)((1S,2...)
Affinity DataIC50:  3.04E+3nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent