BDBM632975 N-(2-chloro-4- (difluoromethyl)thiophen-3-yl)-2-((6- (3,4-dimethylpiperazin-1-yl)-2-methyl- pyrimidin-4-yl)amino)thiazole-5- carboxamide::US20230348453, Compound E13
SMILES CN1CCN(CC1)c1cc(Nc2ncc(s2)C(=O)Nc2c(Cl)scc2C(F)F)nc(C)n1
InChI Key InChIKey=ZATJAIQPRBTMDO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 632975
Affinity DataIC50: <20nMAssay Description:The IC50 for the inhibition of ABL1 by dasatinib, by C7 and by B3 is approximately 1.5 nM, 5.1 nM and 1.6 nM, and of SRC is 1.5 nM, 1.5 nM and 1.5 nM...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The IC50 for the inhibition of ABL1 by dasatinib, by C7 and by B3 is approximately 1.5 nM, 5.1 nM and 1.6 nM, and of SRC is 1.5 nM, 1.5 nM and 1.5 nM...More data for this Ligand-Target Pair