BDBM633252 Preparation of 2-[(R)-3-decanoyloxytetradecanoylamino]ethyl 2,3-di-[(R)-3-decanoyloxytetradecanoylamino]-2,3-dideoxy-4-O-sulfoxy-β-D-allopyranoside ::US11458151, Compound 2

SMILES CCCCCCCCCCC[C@H](CC(=O)NCCO[C@@H]1OC(CO)[C@@H](OS(O)(=O)=O)[C@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCC)C1NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCC)OC(=O)CCCCCCCCC

InChI Key InChIKey=SZMSMMGIEUOERK-RVTCTMKFSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 633252   

TargetToll-like receptor 4(Homo sapiens (Human))
Inimmune

US Patent
LigandPNGBDBM633252(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  64nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633252(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  0.0180nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C motif chemokine 4(Homo sapiens (Human))
Inimmune

US Patent
LigandPNGBDBM633252(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  5.89nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
Inimmune

US Patent
LigandPNGBDBM633252(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  41nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent