BDBM633254 Preparation of N—[(R)-3-Decyloxytetradecanoyl]-O-[2,3-di-[(R)-3-decyloxytetradecanoylamino]-2,3-dideoxy-4-O-phosphono-]-β-D-allopyranosyl]-L-serine ::US11458151, Compound 4::US11458151, Compound 7

SMILES CCCCCCCCCCC[C@H](CC(=O)N[C@@H](CO[C@@H]1OC(CO)[C@@H](OP(O)(O)=O)[C@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCC)C1NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCC)C(O)=O)OC(=O)CCCCCCCCC

InChI Key InChIKey=OXWMTUVXSBTISH-FYBAOWBXSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 633254   

TargetToll-like receptor 4(Homo sapiens (Human))
Inimmune

US Patent
LigandPNGBDBM633254(Preparation of N—[(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  1.32nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
Inimmune

US Patent
LigandPNGBDBM633254(Preparation of N—[(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  1.39nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633254(Preparation of N—[(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  0.00100nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C motif chemokine 4(Homo sapiens (Human))
Inimmune

US Patent
LigandPNGBDBM633254(Preparation of N—[(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  0.124nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
Inimmune

US Patent
LigandPNGBDBM633254(Preparation of N—[(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  0.780nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent