BDBM633255 GLA::Glycopyranoside Lipid A::MPLA::Monophosphoryl Lipid A::Monophosphoryl hexaacyl disaccharide::US11458151, Compound MPL

SMILES CCCCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCC)CC(=O)N[C@H]1[C@H](OC[C@H]2O[C@H](O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H]2O)O[C@H](CO)[C@@H](OP(O)([O-])=O)[C@@H]1OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC

InChI Key InChIKey=JSNQJZJCKAFSHT-OPYGSFAOSA-M

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 633255   

TargetToll-like receptor 4(Homo sapiens (Human))
Inimmune

US Patent
LigandPNGBDBM633255(GLA | Glycopyranoside Lipid A | MPLA | Monophospho...)
Affinity DataEC50:  152nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633255(GLA | Glycopyranoside Lipid A | MPLA | Monophospho...)
Affinity DataEC50:  0.258nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C motif chemokine 4(Homo sapiens (Human))
Inimmune

US Patent
LigandPNGBDBM633255(GLA | Glycopyranoside Lipid A | MPLA | Monophospho...)
Affinity DataEC50:  3.10nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent