BDBM634937 US11814367, Compound 386::US11814367, Compound 777

SMILES CC(C)c1ccc(nc1F)[C@@H](NC(=O)[C@@H]1C[C@@H](F)CN1C(=O)Cn1cc(C)c(=O)n(C)c1=O)c1ccccc1

InChI Key InChIKey=MIQLBDJOBGVDGS-UCFCWBNQSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 634937   

TargetGlycogen [starch] synthase, muscle(Homo sapiens (Human))
Maze Therapeutics

US Patent
LigandPNGBDBM634937(US11814367, Compound 386 | US11814367, Compound 77...)
Affinity DataIC50:  42nMAssay Description:Compounds that inhibit the hGYS1 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen [starch] synthase, muscle(Homo sapiens (Human))
Maze Therapeutics

US Patent
LigandPNGBDBM634937(US11814367, Compound 386 | US11814367, Compound 77...)
Affinity DataIC50:  5nMAssay Description:Compounds that inhibit the hGYS1 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen [starch] synthase, liver(Homo sapiens)
Maze Therapeutics

US Patent
LigandPNGBDBM634937(US11814367, Compound 386 | US11814367, Compound 77...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen [starch] synthase, liver(Homo sapiens)
Maze Therapeutics

US Patent
LigandPNGBDBM634937(US11814367, Compound 386 | US11814367, Compound 77...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent