BDBM634942 US11814367, Compound 391

SMILES CC(C)c1ccc(nc1F)[C@@H](NC(=O)[C@@H]1C[C@@H](F)CN1C(=O)Cc1cccn2c1n[nH]c2=O)c1ccccc1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 634942   

TargetGlycogen [starch] synthase, muscle(Homo sapiens (Human))
Maze Therapeutics

US Patent
LigandPNGBDBM634942(US11814367, Compound 391)
Affinity DataIC50:  6nMAssay Description:Compounds that inhibit the hGYS1 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen [starch] synthase, liver(Homo sapiens)
Maze Therapeutics

US Patent
LigandPNGBDBM634942(US11814367, Compound 391)
Affinity DataIC50:  8.93E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent