BDBM636876 N-(4-(5-(6-morpholinopyridin-2-yl)-1H- imidazol-2-yl)-3-(6-azaspiro[2.5]octan-6- yl)phenyl)methanesulfonamide::US20230382889, Compound 10
SMILES CS(=O)(=O)Nc1ccc(-c2ncc([nH]2)-c2cccc(n2)N2CCOCC2)c(c1)N1CCC2(CC2)CC1
InChI Key InChIKey=IIRJNQGATGGQNF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 636876
Affinity DataKi: 14nMAssay Description:Compound binding kinetics parameters (kon and koff) were determined by the method of global progress curve analysis (GPCA). KIF18A (0.25 nM) was incu...More data for this Ligand-Target Pair
Affinity DataIC50: 9.20nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair