BDBM637108 US20230382904, Compound 28::US20230382904, Compound 47::US20230382904, Compound 48
SMILES C[C@H](NC(=O)c1cc(cs1)-c1cc(C(=O)NC2CNC(=O)C2)c2nc(N)nn2c1)c1ccc(F)cc1
InChI Key InChIKey=WEFXAEVNJQWAFZ-WHUIICBVSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 637108
Affinity DataIC50: 3.40nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 13(Homo sapiens (Human))
The Johns Hopkins University
US Patent
The Johns Hopkins University
US Patent
Affinity DataIC50: 110nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 13(Homo sapiens (Human))
The Johns Hopkins University
US Patent
The Johns Hopkins University
US Patent
Affinity DataIC50: 77nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 13(Homo sapiens (Human))
The Johns Hopkins University
US Patent
The Johns Hopkins University
US Patent
Affinity DataIC50: 3.60E+3nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair