BDBM637108 US20230382904, Compound 28::US20230382904, Compound 47::US20230382904, Compound 48

SMILES C[C@H](NC(=O)c1cc(cs1)-c1cc(C(=O)NC2CNC(=O)C2)c2nc(N)nn2c1)c1ccc(F)cc1

InChI Key InChIKey=WEFXAEVNJQWAFZ-WHUIICBVSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 637108   

TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637108(US20230382904, Compound 28 | US20230382904, Compou...)
Affinity DataIC50:  3.40nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 13(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637108(US20230382904, Compound 28 | US20230382904, Compou...)
Affinity DataIC50:  110nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 13(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637108(US20230382904, Compound 28 | US20230382904, Compou...)
Affinity DataIC50:  77nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 13(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637108(US20230382904, Compound 28 | US20230382904, Compou...)
Affinity DataIC50:  3.60E+3nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637108(US20230382904, Compound 28 | US20230382904, Compou...)
Affinity DataIC50:  2.40nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637108(US20230382904, Compound 28 | US20230382904, Compou...)
Affinity DataIC50:  130nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent