BDBM637123 US20230382904, Compound 43::US20230382904, Compound 71::US20230382904, Compound 72
SMILES C[C@H](NC(=O)c1cc(cs1)-c1cc(C(=O)NC(C)C(F)(F)F)c2nc(N)nn2c1)c1ccccc1
InChI Key InChIKey=DMZWCKPQTKYLBB-UEWDXFNNSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 637123
Affinity DataIC50: 22nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 13(Homo sapiens (Human))
The Johns Hopkins University
US Patent
The Johns Hopkins University
US Patent
Affinity DataIC50: 130nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 13(Homo sapiens (Human))
The Johns Hopkins University
US Patent
The Johns Hopkins University
US Patent
Affinity DataIC50: 6.20E+3nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 13(Homo sapiens (Human))
The Johns Hopkins University
US Patent
The Johns Hopkins University
US Patent
Affinity DataIC50: 55nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Affinity DataIC50: 4.85nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair