BDBM640345 8-amino-N-cyclopropyl-5-(4-(1-(2-(4- methylpiperazin-1-yl)-2-oxoethyl)-1H- pyrazole-4-yl)phenyl)-1,7- naphthyridine-3-carboxamide::US11840531, Compound 3.47

SMILES CN1CCN(CC1)C(=O)Cn1cc(cn1)-c1ccc(cc1)-c1cnc(N)c2ncc(cc12)C(=O)NC1CC1

InChI Key InChIKey=QHBWJWFTGGEZJF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640345   

TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Joint Stock Company “Biocad”

US Patent
LigandPNGBDBM640345(8-amino-N-cyclopropyl-5-(4-(1-(2-(4- methylpiperaz...)
Affinity DataIC50:  1.10nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent