BDBM640351 2-(4-(4-(8-amino-3-(azetidine-1- carbonyl)-1,7-naphthyridine-5- yl)phenyl)-1H-pyrazole-1-yl)-1-(4- methylpiperazine-1-yl)ethan-1-one::US11840531, Compound 3.53

SMILES CN1CCN(CC1)C(=O)Cn1cc(cn1)-c1ccc(cc1)-c1cnc(N)c2ncc(cc12)C(=O)N1CCC1

InChI Key InChIKey=MVOSRUHPDXQVHO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640351   

TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Joint Stock Company “Biocad”

US Patent
LigandPNGBDBM640351(2-(4-(4-(8-amino-3-(azetidine-1- carbonyl)-1,7-nap...)
Affinity DataIC50:  1.01nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent