BDBM640352 (8-amino-5-(4-(1-(2-methoxyethyl)- 1H-pyrazole-4-yl)phenyl)-1,7- naphthyridin-3-yl) (azetidin-1- yl)methanone::US11840531, Compound 3.54

SMILES COCCn1cc(cn1)-c1ccc(cc1)-c1cnc(N)c2ncc(cc12)C(=O)N1CCC1

InChI Key InChIKey=AZHQADPVOIAAEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640352   

TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Joint Stock Company “Biocad”

US Patent
LigandPNGBDBM640352((8-amino-5-(4-(1-(2-methoxyethyl)- 1H-pyrazole-4-y...)
Affinity DataIC50:  1.27nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent