BDBM640353 8-amino-5-(4-(1-(2-(dimethylamino)- 2-oxoethyl)-1H-pyrazole-4-yl) phenyl- N-(2-methoxyethyl)-N-methyl-1,7- naphthyridine-3-carboxamide::US11840531, Compound 3.55

SMILES COCCN(C)C(=O)c1cnc2c(N)ncc(-c3ccc(cc3)-c3cnn(CC(=O)N(C)C)c3)c2c1

InChI Key InChIKey=RAGVYQVNVQXWCA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640353   

TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Joint Stock Company “Biocad”

US Patent
LigandPNGBDBM640353(8-amino-5-(4-(1-(2-(dimethylamino)- 2-oxoethyl)-1H...)
Affinity DataIC50:  1.24nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent