BDBM640592 US20230399319, Example 2-141

SMILES Cc1ccc(cc1Nc1nc(co1)C(=O)NS(=O)(=O)N1CCCC(CC1)C#N)C(F)(F)F

InChI Key InChIKey=PRMXTQUHNRYNKI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640592   

TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Japan Tobacco

US Patent
LigandPNGBDBM640592(US20230399319, Example 2-141)
Affinity DataIC50:  9.70nMAssay Description:The NLRP3 inflammasome inhibitory activity of test compounds were evaluated CM the basis of the inhibitory activity of the IL-1β, production in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent