BDBM6409 N-(3-chlorophenyl)-6-(5-{[3-(morpholin-4-yl)propyl]amino}pyridin-3-yl)pyrazin-2-amine::N-[5-[6-[(3-Chlorophenyl)amino]pyrazinyl]-3-pyridinyl]-4-morpholinepropanamine::Pyrazine-Pyridine Biheteroaryl 52

SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCN3CCOCC3)c2)c1

InChI Key InChIKey=ILIYEHQBHWMGTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6409   

TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6409(N-(3-chlorophenyl)-6-(5-{[3-(morpholin-4-yl)propyl...)
Affinity DataIC50:  180nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6409(N-(3-chlorophenyl)-6-(5-{[3-(morpholin-4-yl)propyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed