BDBM641308 US11845723, Example 202

SMILES COc1ccc(cc1)-c1cccc(c1)N(C)c1nc2nncn2c2cc(CO)ccc12

InChI Key InChIKey=XLYOVHISSYLGMI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 641308   

TargetDiacylglycerol kinase alpha(Homo sapiens)
Gilead Sciences

US Patent
LigandPNGBDBM641308(US11845723, Example 202)
Affinity DataIC50:  5.90nMAssay Description:Table 6: Alternatively, the enzymatic activity of human DGKα was monitored in a biochemical assay in the presence or absence of compounds and us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol kinase alpha(Homo sapiens)
Gilead Sciences

US Patent
LigandPNGBDBM641308(US11845723, Example 202)
Affinity DataIC50:  4nMAssay Description:Table 5: The IC50 value was calculated via a regression analysis of the inhibition rate (%) measured from the intensity of the luminescence at each c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent