BDBM6423 3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}-6-fluoropyridin-3-yl)amino]propan-1-ol::3-{5-[6-(3-Chloro-phenylamino)-pyrazin-2-yl]-6-fluoropyridin-3-ylamino}-propan-1-ol::Pyrazine-Pyridine Biheteroaryl 70

SMILES OCCCNc1cnc(F)c(c1)-c1cncc(Nc2cccc(Cl)c2)n1

InChI Key InChIKey=CWLYLDIPBOBIFQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6423   

TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6423(3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}-6-fl...)
Affinity DataIC50:  251nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6423(3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}-6-fl...)
Affinity DataIC50: >1.00E+4nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed