BDBM647340 4-(7-(1-ethyl-1H- pyrazol-4- yl)imidazo[1,2- a]pyridin-3-yl)-2- methylbenzonitrile::US20240025892, Example 47
SMILES CCn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(C#N)c(C)c1
InChI Key InChIKey=RXHXLESLBWUVQS-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 647340
Affinity DataIC50: 0.855nMAssay Description:Assays were performed in base reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL BSA, 0.1 mM Na3VO4, 2 mM DTT, 1...More data for this Ligand-Target Pair
Affinity DataIC50: 8.34nMAssay Description:Assays were performed in base reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL BSA, 0.1 mM Na3VO4, 2 mM DTT, 1...More data for this Ligand-Target Pair
Affinity DataIC50: 4.16nMAssay Description:Assays were performed in base reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL BSA, 0.1 mM Na3VO4, 2 mM DTT, 1...More data for this Ligand-Target Pair