BDBM647346 2-(4-(6-(1- cyclopropyl-1H- pyrazol-4- yl)pyrazolo[1,5- a]pyridin-3-yl)-2,6- dimethoxyphenyl)- 5-ethyl-1,3,4- oxadiazole::US20240025892, Example 53
SMILES CCc1nnc(o1)-c1c(OC)cc(cc1OC)-c1cnn2cc(ccc12)-c1cnn(c1)C1CC1
InChI Key InChIKey=XVNZURGXHLXJIR-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 647346
Affinity DataIC50: 1.77nMAssay Description:Assays were performed in base reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL BSA, 0.1 mM Na3VO4, 2 mM DTT, 1...More data for this Ligand-Target Pair
Affinity DataIC50: 17.4nMAssay Description:Assays were performed in base reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL BSA, 0.1 mM Na3VO4, 2 mM DTT, 1...More data for this Ligand-Target Pair
Affinity DataIC50: 2.62nMAssay Description:Assays were performed in base reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL BSA, 0.1 mM Na3VO4, 2 mM DTT, 1...More data for this Ligand-Target Pair