BDBM651264 6-[3-fluoro-4-(2-methoxypyridin-4-yl)phenyl]-4,5-dihydropyridazin-3(2H)-one::US11897867, Example 32

SMILES COc1cc(ccn1)-c1ccc(cc1F)C1=NNC(=O)CC1

InChI Key InChIKey=QIGADPUVUYRGMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 651264   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651264(6-[3-fluoro-4-(2-methoxypyridin-4-yl)phenyl]-4,5-d...)
Affinity DataIC50:  36nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651264(6-[3-fluoro-4-(2-methoxypyridin-4-yl)phenyl]-4,5-d...)
Affinity DataIC50:  64nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent