BDBM6543 3-quinolinecarbonitrile deriv. 8a::4-(2,4-dichlorophenoxy)-7-[(E)-2-(pyridin-4-yl)ethenyl]quinoline-3-carbonitrile

SMILES Clc1ccc(Oc2c(cnc3cc(\C=C\c4ccncc4)ccc23)C#N)c(Cl)c1

InChI Key InChIKey=KCBAYBBHBINUKT-OWOJBTEDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6543   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM6543(3-quinolinecarbonitrile deriv. 8a | 4-(2,4-dichlor...)
Affinity DataIC50:  380nMAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed