BDBM686 BMS-186318 analog 23::[1S-[1R*,2S*(2S*,3R*)]]-[3-[[3-[[(1,10-Dimethylethoxy)carbonyl]amino]-2-hydroxy-4-[4-[[(4-morpholinyl-carbonyl)oxy]methyl]phenyl]butyl]amino]-2-::hydroxy-1-(phenylmethyl)propyl]carbamic Acid, 1,1-Dimethylethyl Ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNC[C@@H](O)[C@H](Cc1ccc(COC(=O)N2CCOCC2)cc1)NC(=O)OC(C)(C)C

InChI Key InChIKey=DDHUVWKEFAMGRB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol-Myers Squibb

LigandPNGBDBM686([1S-[1R*,2S*(2S*,3R*)]]-[3-[[3-[[(1,10-Dimethyleth...)
Affinity DataIC50: 30nMpH: 5.5 T: 2°CAssay Description:IC50 values are determined by inhibition of the cleavage of the peptidic substrate [V-S-Q-N-(beta-naphthylalanine)-P-I-V]. The IC50 value represents ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed