BDBM69679 Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethyl)-amine::MLS001207641::N,N-dimethyl-2-(5-naphtho[2,1-g][1,3]benzodioxolyl)ethanamine;hydrochloride::N,N-dimethyl-2-naphtho[2,1-g][1,3]benzodioxol-5-yl-ethanamine;hydrochloride::N,N-dimethyl-2-naphtho[2,1-g][1,3]benzodioxol-5-ylethanamine;hydrochloride::SMR000517938::US9211296, Table 7, Compd: 10::cid_24746882::dimethyl(2-naphtho[2,1-g][1,3]benzodioxol-5-ylethyl)amine;hydrochloride

SMILES CN(C)CCc1cc2OCOc2c2c1ccc1ccccc21

InChI Key InChIKey=FXTBDJZGDJJCQU-UHFFFAOYSA-N

Data  4 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 69679   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM69679(Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]-raclopride from D2 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM69679(Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]-raclopride from D2 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM69679(Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...)
Affinity DataKi:  4.13E+3nMAssay Description:Displacement of [3H]-SCH23390 from D1 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM69679(Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...)
Affinity DataKi:  4.14E+3nMAssay Description:Displacement of [3H]-SCH23390 from D1 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM69679(Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...)
Affinity DataIC50: >9.90E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetDNA polymerase(Vaccinia virus (strain WR))
University of Pennsylvania

US Patent
LigandPNGBDBM69679(Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...)
Affinity DataIC50:  5.40E+3nMpH: 7.4 T: 2°CAssay Description:A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM69679(Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...)
Affinity DataEC50:  2.59E+4nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay