BDBM725 Boc-Monopyrrolinone Inhibitor::Pyrrolinone deriv. 6::Pyrrolinone inhibitor 6::tert-butyl N-[(2S,3S)-4-[(2S)-2-benzyl-4-[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-3-oxo-2,3-dihydro-1H-pyrrol-2-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamate

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C[C@]1(Cc2ccccc2)N=CC(C2[C@H](O)Cc3ccccc23)C1=O

InChI Key InChIKey=XGMFGBHGPVJDEB-OZFQOWRPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 725   

TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM725(Boc-Monopyrrolinone Inhibitor | Pyrrolinone deriv....)
Affinity DataIC50:  11.9nMpH: 5.5 T: 2°CAssay Description:All enzyme assays were performed under initial velocity and steady-state conditions. The conditions for the enzyme catalyzed hydrolysis of the cleava...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed