BDBM7377 4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol::6-phenyl[5H]pyrrolo[2,3-b]pyrazine (aloisine) 39::7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine::CHEMBL75680::aloisine A

SMILES CCCCc1c([nH]c2nccnc12)-c1ccc(O)cc1

InChI Key InChIKey=PRIGRJPRGZCFAS-UHFFFAOYSA-N

Data  14 IC50  3 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7377   

TargetGlycogen synthase kinase-3(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM7377(4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol | ...)
Affinity DataIC50:  650nMAssay Description:Inhibition of GSK3alpha/beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM7377(4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol | ...)
Affinity DataIC50:  150nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM7377(4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol | ...)
Affinity DataIC50:  200nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair