BDBM74208 2,4-bis(oxidanyl)benzoic acid::2,4-dihydroxybenzoic acid::MLS001055408::SMR001227190::beta-Resorcylic acid::cid_1491

SMILES OC(=O)c1ccc(O)cc1O

InChI Key InChIKey=UIAFKZKHHVMJGS-UHFFFAOYSA-N

Data  7 KI  1 IC50  1 EC50

PDB links: 3 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 74208   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM74208(2,4-bis(oxidanyl)benzoic acid | 2,4-dihydroxybenzo...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM74208(2,4-bis(oxidanyl)benzoic acid | 2,4-dihydroxybenzo...)
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM74208(2,4-bis(oxidanyl)benzoic acid | 2,4-dihydroxybenzo...)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM74208(2,4-bis(oxidanyl)benzoic acid | 2,4-dihydroxybenzo...)
Affinity DataKi:  6.80E+4nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM74208(2,4-bis(oxidanyl)benzoic acid | 2,4-dihydroxybenzo...)
Affinity DataKi:  7.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM74208(2,4-bis(oxidanyl)benzoic acid | 2,4-dihydroxybenzo...)
Affinity DataKi:  7.20E+4nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Gallus gallus (Chicken))
University Of Oulu

LigandPNGBDBM74208(2,4-bis(oxidanyl)benzoic acid | 2,4-dihydroxybenzo...)
Affinity DataKi:  5.30E+5nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-(1,3)-fucosyltransferase 7(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM74208(2,4-bis(oxidanyl)benzoic acid | 2,4-dihydroxybenzo...)
Affinity DataIC50: >2.00E+5nMpH: 7.3 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein LANA1(Human herpesvirus 8)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM74208(2,4-bis(oxidanyl)benzoic acid | 2,4-dihydroxybenzo...)
Affinity DataEC50: >7.50E+4nMAssay Description:Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay