BDBM77944 US10245267, Example 381::US10709712, Example 381::US9694016, 381
SMILES Cc1cc(C(=O)Nc2ccc(C)c(c2)-c2cc(N3CCOCC3)c(=O)n(C)c2)n(C)n1
InChI Key InChIKey=MVCSKNRBGKDLBT-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 77944
Affinity DataIC50: 25.5nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair