BDBM79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566

SMILES CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1

InChI Key InChIKey=ZEWQUBUPAILYHI-UHFFFAOYSA-N

Data  71 KI  22 IC50  6 Kd

PDB links: 7 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 79181   

TargetCalmodulin-1(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM79181(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to calmodulin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalmodulin-1(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM79181(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)
Affinity DataIC50:  1.11E+3nMAssay Description:The competition binding assay was performed in a 384-well plate format and in 20 μl reactions. Serial dilutions (0.001-100 μM) of a test co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalmodulin-1(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM79181(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)
Affinity DataIC50:  1.06E+3nMAssay Description:The competition binding assay was performed in a 384-well plate format and in 20 μl reactions. Serial dilutions (0.001-100 μM) of a test co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalmodulin-1(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM79181(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)
Affinity DataIC50:  1.06E+3nMAssay Description:The competition binding assay was performed in a 384-well plate format and in 20 μl reactions. Serial dilutions (0.001-100 μM) of a test co...More data for this Ligand-Target Pair
In DepthDetails US Patent