BDBM81424 N-(4-methoxyphenyl)-2-(3-methyl-4-oxo-3,4-dihydrophthalazin-1-yl)acetamide, Compound D

SMILES COc1ccc(NC(=O)Cc2nn(C)c(=O)c3ccccc23)cc1

InChI Key InChIKey=OLBJIULZJKWFBM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 81424   

TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM81424(N-(4-methoxyphenyl)-2-(3-methyl-4-oxo-3,4-dihydrop...)
Affinity DataIC50: 930nMAssay Description:Inhibition of recombinant Cryptosporidium parvum IMPDH assessed as production of NADH by fluorescence assay in presence of 0.05% BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM81424(N-(4-methoxyphenyl)-2-(3-methyl-4-oxo-3,4-dihydrop...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant Cryptosporidium parvum IMPDH assessed as production of NADH by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase(Borrelia burgdorferi)
Brandeis University

LigandPNGBDBM81424(N-(4-methoxyphenyl)-2-(3-methyl-4-oxo-3,4-dihydrop...)
Affinity DataIC50: 1.70E+3nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase(Helicobacter pylori (strain G27))
Brandeis University

LigandPNGBDBM81424(N-(4-methoxyphenyl)-2-(3-methyl-4-oxo-3,4-dihydrop...)
Affinity DataIC50: 3.00E+3nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM81424(N-(4-methoxyphenyl)-2-(3-methyl-4-oxo-3,4-dihydrop...)
Affinity DataIC50: 5.40E+3nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase(Streptococcus pyogenes (Firmicutes))
Brandeis University

LigandPNGBDBM81424(N-(4-methoxyphenyl)-2-(3-methyl-4-oxo-3,4-dihydrop...)
Affinity DataIC50: 4.90E+4nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed