BDBM8228 3-[(3-chlorophenyl)amino]-4-(3-methoxyphenyl)-2,5-dihydro-1H-pyrrole-2,5-dione::4-arylmaleimide deriv. 6k

SMILES COc1cccc(c1)C1=C(Nc2cccc(Cl)c2)C(=O)NC1=O

InChI Key InChIKey=IKLOROWNYFUEKV-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 8228   

TargetSTE20-like serine/threonine-protein kinase(Homo sapiens (Human))
University Of Campinas (Unicamp)

Curated by ChEMBL
LigandPNGBDBM8228(3-[(3-chlorophenyl)amino]-4-(3-methoxyphenyl)-2,5-...)
Affinity DataKi:  120nMAssay Description:Binding affinity human SLK by binding displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 10(Homo sapiens (Human))
University Of Campinas (Unicamp)

Curated by ChEMBL
LigandPNGBDBM8228(3-[(3-chlorophenyl)amino]-4-(3-methoxyphenyl)-2,5-...)
Affinity DataKi:  950nMAssay Description:Binding affinity human STK10 by binding displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM8228(3-[(3-chlorophenyl)amino]-4-(3-methoxyphenyl)-2,5-...)
Affinity DataIC50:  257nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM8228(3-[(3-chlorophenyl)amino]-4-(3-methoxyphenyl)-2,5-...)
Affinity DataIC50:  257nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed