BDBM837 Benzocycloalkyl Amines deriv. 7::tert-butyl N-[(2S,3S,5R)-5-benzyl-5-{bicyclo[4.2.0]octa-1,3,5-trien-7-ylcarbamoyl}-3-hydroxy-1-phenylpentan-2-yl]carbamate
SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)NC1Cc2ccccc12
InChI Key InChIKey=HPNWNQXCBHLAEF-QTRRWBPYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 837
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories
Merck Sharp and Dohme Research Laboratories
Affinity DataIC50: 22nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair