BDBM83846 5-(2-(dimethylamino)ethylamino)-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one::MLS002701556::SMR001565157::cid_371509

SMILES Cl.CN(C)CCNc1ccc2ncn3c2c1c(=O)c1cc(O)ccc31

InChI Key InChIKey=NXTYWYBBZCKFPD-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 83846   

TargetOrotidine 5'-phosphate decarboxylase(Aspergillus niger)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM83846(5-(2-(dimethylamino)ethylamino)-8-hydroxy-6H-imida...)
Affinity DataEC50: >6.62E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM83846(5-(2-(dimethylamino)ethylamino)-8-hydroxy-6H-imida...)
Affinity DataEC50:  1.15E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM83846(5-(2-(dimethylamino)ethylamino)-8-hydroxy-6H-imida...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM83846(5-(2-(dimethylamino)ethylamino)-8-hydroxy-6H-imida...)
Affinity DataIC50:  296nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM83846(5-(2-(dimethylamino)ethylamino)-8-hydroxy-6H-imida...)
Affinity DataIC50:  83nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed