BDBM84524 Sulindac analogue, 21

SMILES CC1=C(CC(O)=O)c2ccc(Br)cc2\C1=C/c1ccoc1

InChI Key InChIKey=ZBOCJDCPGUKFJE-NSIKDUERSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 84524   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Max-Planck-Institut FÜR Molekulare Physiologie

LigandPNGBDBM84524(Sulindac analogue, 21)
Affinity DataIC50:  2.40E+4nMAssay Description:The kinase-catalyzed phosphorylation of poly(Glu4-Tyr) in the presence of varying concentrations of inhibitor was determined. The kinase were employ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Max-Planck-Institut FÜR Molekulare Physiologie

LigandPNGBDBM84524(Sulindac analogue, 21)
Affinity DataIC50:  1.50E+4nMAssay Description:The kinase-catalyzed phosphorylation of poly(Glu4-Tyr) in the presence of varying concentrations of inhibitor was determined. The kinase were employ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Max-Planck-Institut FÜR Molekulare Physiologie

LigandPNGBDBM84524(Sulindac analogue, 21)
Affinity DataIC50:  3.00E+3nMAssay Description:The kinase-catalyzed phosphorylation of poly(Glu4-Tyr) in the presence of varying concentrations of inhibitor was determined. The kinase were employ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Max-Planck-Institut FÜR Molekulare Physiologie

LigandPNGBDBM84524(Sulindac analogue, 21)
Affinity DataIC50:  1.30E+4nMAssay Description:The kinase-catalyzed phosphorylation of poly(Glu4-Tyr) in the presence of varying concentrations of inhibitor was determined. The kinase were employ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Max-Planck-Institut FÜR Molekulare Physiologie

LigandPNGBDBM84524(Sulindac analogue, 21)
Affinity DataIC50:  2.20E+4nMAssay Description:The kinase-catalyzed phosphorylation of poly(Glu4-Tyr) in the presence of varying concentrations of inhibitor was determined. The kinase were employ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed