BDBM84698 Quinolinone derivative, 9

SMILES Cc1ccc(cc1)S(=O)(=O)N1C(\C(=C/c2ccc(O)c(O)c2)C(=O)c2ccccc12)c1ccc(O)c(O)c1

InChI Key InChIKey=AWDUUUPCCHYXER-HYARGMPZSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 84698   

TargetTrans-sialidase(Trypanosoma cruzi)
University of British Columbia

LigandPNGBDBM84698(Quinolinone derivative, 9)
Affinity DataKi:  400nM ΔG°:  -9.01kcal/mole IC50:  600nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using trans-sialidase, a membrane-associated protein.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Sao Paulo

Curated by ChEMBL
LigandPNGBDBM84698(Quinolinone derivative, 9)
Affinity DataIC50:  600nMAssay Description:Inhibition of Trypanosoma cruzi trans-sialidase using Trifluoromethylumbelliferyl alpha-sialoside as substrate by UV/visible spectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed