BDBM8529 (3S)-oxolan-3-yl N-[(2S,3S)-4-[(2S)-2-benzyl-4-[(3R)-3-(carbamoylmethyl)-2,3-dihydro-1H-inden-1-yl]-3-oxo-2,3-dihydro-1H-pyrrol-2-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamate::monopyrrolinone-based inhibitor (+)-4::monopyrrolinone-based inhibitor 4

SMILES NC(=O)C[C@H]1CC(C2C=N[C@](C[C@H](O)[C@H](Cc3ccccc3)NC(=O)O[C@H]3CCOC3)(Cc3ccccc3)C2=O)c2ccccc12

InChI Key InChIKey=WBFJMNVDJSNRDC-BXJLQUFPSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8529   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM8529((3S)-oxolan-3-yl N-[(2S,3S)-4-[(2S)-2-benzyl-4-[(3...)
Affinity DataIC50:  2.40nMpH: 5.5 T: 2°CAssay Description:The inhibition of HIV-1 protease activities were measured with peptide hydrolysis assays. The appearance of products and the corresponding loss of su...More data for this Ligand-Target Pair