BDBM8586 (3-Pyridylmethylene)indane 5a::3-{[(1E)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]methyl}pyridine

SMILES Fc1ccc2\C(CCc2c1)=C\c1cccnc1

InChI Key InChIKey=WLUDJBASYYHRDC-XYOKQWHBSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 8586   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8586((3-Pyridylmethylene)indane 5a | 3-{[(1E)-5-fluoro-...)
Affinity DataIC50:  311nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Calcutta

Curated by ChEMBL
LigandPNGBDBM8586((3-Pyridylmethylene)indane 5a | 3-{[(1E)-5-fluoro-...)
Affinity DataIC50:  2.54E+3nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Calcutta

Curated by ChEMBL
LigandPNGBDBM8586((3-Pyridylmethylene)indane 5a | 3-{[(1E)-5-fluoro-...)
Affinity DataIC50:  2.54E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8586((3-Pyridylmethylene)indane 5a | 3-{[(1E)-5-fluoro-...)
Affinity DataIC50:  7nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed